At first,download and run Microsoft's Malicious Removal tool:http://www.microsoft.com/security/malwareremove/default.mspx
This will make sure no widely spread and well-known rootkits and bots are present there.
Then check this thread out for a list of possible forums,
where people can provide you with exact disinfection instructions:http://www.malwaredomainlist.com/forums/index.php?topic=40.0
As a personal suggestion,I would recommend asking for assistance over at MalwareBytes' forum,
as they're specializing exactly in the removal of infections caused by rogue software etc.http://www.malwarebytes.org/forums/
For a variety of reasons,we don't "officially" provide disinfection advises for pc end-users,
only for servers that got hacked etc...
But if nothing from the above solves the problem,then please,
do not hesitate to ask back here again for help:
someone will take over your case specifically and help you remove the nasties from there.